DNA Cleavage

A synthetic dinuclear copper (II) hydrolase and its potential as antitumoral: Cytotoxicity, cellular uptake, and DNA cleavage

Inorganic Chemistry / Kinetics / Inorganic / Cytotoxicity / Humans / Copper / Mice / Female / Animals / Male / Cytotoxic Activity / DNA binding / Neoplasms / DNA Cleavage / Inorganic Biochemistry / Aqueous Solution / Organometallic Compounds / Cell Survival / Kinetic Parameter / Antineoplastic Agents / Plasmid DNA / Cell Growth / Copper / Mice / Female / Animals / Male / Cytotoxic Activity / DNA binding / Neoplasms / DNA Cleavage / Inorganic Biochemistry / Aqueous Solution / Organometallic Compounds / Cell Survival / Kinetic Parameter / Antineoplastic Agents / Plasmid DNA / Cell Growth

A synthetic dinuclear copper(II) hydrolase and its potential as antitumoral: cytotoxicity, cellular uptake, and DNA cleavage

Inorganic Chemistry / Kinetics / Inorganic / Humans / Copper / Mice / Female / Animals / Male / Cytotoxic Activity / DNA binding / Neoplasms / DNA Cleavage / Inorganic Biochemistry / Aqueous Solution / Organometallic Compounds / Cell Survival / Kinetic Parameter / Antineoplastic Agents / Plasmid DNA / Cell Growth / Mice / Female / Animals / Male / Cytotoxic Activity / DNA binding / Neoplasms / DNA Cleavage / Inorganic Biochemistry / Aqueous Solution / Organometallic Compounds / Cell Survival / Kinetic Parameter / Antineoplastic Agents / Plasmid DNA / Cell Growth

Identification of a novel human mitochondrial endo-/exonuclease Ddk1/c20orf72 necessary for maintenance of proper 7S DNA levels

Mitochondria / Gene expression / Biological Sciences / Phylogeny / Environmental Sciences / Mitochondrial DNA / Humans / Nucleic Acids / Protein Secondary Structure Prediction / HeLa cells / DNA Cleavage / Amino Acid Substitution Rates / Hydrogen-Ion Concentration / Protein Transport / Mitochondrial DNA / Humans / Nucleic Acids / Protein Secondary Structure Prediction / HeLa cells / DNA Cleavage / Amino Acid Substitution Rates / Hydrogen-Ion Concentration / Protein Transport

Identification of a novel human mitochondrial endo-/exonuclease Ddk1/c20orf72 necessary for maintenance of proper 7S DNA levels

Mitochondria / Gene expression / Biological Sciences / Phylogeny / Environmental Sciences / Mitochondrial DNA / Humans / Nucleic Acids / Protein Secondary Structure Prediction / HeLa cells / DNA Cleavage / Amino Acid Substitution Rates / Hydrogen-Ion Concentration / Protein Transport / Mitochondrial DNA / Humans / Nucleic Acids / Protein Secondary Structure Prediction / HeLa cells / DNA Cleavage / Amino Acid Substitution Rates / Hydrogen-Ion Concentration / Protein Transport

Identification of a novel human mitochondrial endo-/exonuclease Ddk1/c20orf72 necessary for maintenance of proper 7S DNA levels

Mitochondria / Gene expression / Biological Sciences / Phylogeny / Environmental Sciences / Mitochondrial DNA / Humans / Nucleic Acids / Protein Secondary Structure Prediction / HeLa cells / DNA Cleavage / Amino Acid Substitution Rates / Hydrogen-Ion Concentration / Protein Transport / Mitochondrial DNA / Humans / Nucleic Acids / Protein Secondary Structure Prediction / HeLa cells / DNA Cleavage / Amino Acid Substitution Rates / Hydrogen-Ion Concentration / Protein Transport

DNA targeting polyaza macrobicyclic dizinc(ii) complexes promoting high in vitro caspase dependent anti-proliferative activity against human carcinoma cancer cells

Biochemistry / Inorganic Chemistry / DNA / Humans / Zinc / Caspase / Carcinoma / HeLa cells / Neoplasms / DNA Cleavage / Cell Proliferation / Bovine Serum Albumin / Cell Survival / Antineoplastic Agents / Caspase / Carcinoma / HeLa cells / Neoplasms / DNA Cleavage / Cell Proliferation / Bovine Serum Albumin / Cell Survival / Antineoplastic Agents

A synthetic dinuclear copper(II) hydrolase and its potential as antitumoral: cytotoxicity, cellular uptake, and DNA cleavage

Inorganic Chemistry / Kinetics / Inorganic / Cytotoxicity / Humans / Copper / Mice / Female / Animals / Male / Cytotoxic Activity / DNA binding / Neoplasms / DNA Cleavage / Inorganic Biochemistry / Aqueous Solution / Organometallic Compounds / Cell Survival / Kinetic Parameter / Antineoplastic Agents / Plasmid DNA / Cell Growth / Copper / Mice / Female / Animals / Male / Cytotoxic Activity / DNA binding / Neoplasms / DNA Cleavage / Inorganic Biochemistry / Aqueous Solution / Organometallic Compounds / Cell Survival / Kinetic Parameter / Antineoplastic Agents / Plasmid DNA / Cell Growth

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